A 10 kHz pulsed X-ray generator utilising a hot-cathode triode in conjunction with a new type of grid control device for controlling X-ray duration is described. The energy-storage condenser was charged up to 70 kV by a power supply, and the electric charges in the condenser were discharged to the X-ray tube repetitively by the grid control device. The maximum values of the grid voltage, the tube voltage, and the tube current were −1.5 kV, 70 kV, and 0.4 A, respectively. (...) The duration of the flash X-ray pulse was primarily determined by the time constant of the grid control device and the cut-off voltage of thermoelectrons. The X-ray duration was controlled within a region of less than 1 ms; the X-ray intensity with a pulse width of 0.27 ms, a charged voltage of 70 kV, and a peak tube current of 0.4 A was 0.92 μC kg −1 at 0.5 m per pulse. The maximum repetition rate was about 10 kHz, and the size of the focal spot was about 3.5×3.5 mm. (shrink)

Strong evidence shows that exposure and engagement with the natural world not only improve human wellbeing but can also help promote environmentally friendly behaviors. Human-nature relationships are at the heart of global agendas promoted by international organizations including the World Health Organization’s “One Health” and the United Nations “Ocean Decade.” These agendas demand collaborative multisector interdisciplinary efforts at local, national, and global levels. However, while global agendas highlight global goals for a sustainable world, developing science that directly addresses these agendas (...) from design through to delivery and outputs does not come without its challenges. In this article, we present the outcomes of international meetings between researchers, stakeholders, and policymakers from the United Kingdom and Brazil. We propose a model for interdisciplinary work under such global agendas, particularly the interface between One Health and the UN Ocean Decade and identify three priority research areas closely linked to each other: human-nature connection, conservation-human behavior, and implementation strategies. We also discuss a number of recommendations for moving forward. (shrink)

Ascidian tadpole larvae, composed of only about 2500 cells, have a primitive nervous system which is derived from the neural plate. The stereotyped cell cleavage pattern and well characterized cell lineage in these animals allow the isolation and culture of identified blastomeres in variable combinations. Ascidian embryos express cell‐type‐specific markers corresponding to their cell fates, even when cultured under cleavage‐arrest by cytochalasin B. This system provides us with a unique opportunity to study the roles of cell lineage and cell contact (...) in early neuronal differentiation in the absence of events associated with complex morphogenesis. In addition, the isolated, cleavage‐arrested blastomeres are ideally suited to electrical recording, permitting the use of ionic channels as specific markers for differentiation. In the cleavage‐arrested embryos, suppression of one type of K+ channel, and induction of two types of Na+ channels, occur following cell contact with the vegetal blastomere. The combination of molecular and electrophysiological analyses on this simple animal system may provide insights into the nature of the cell interactions important in early neurogenesis, both in ascidians and in vertebrates. (shrink)

生殖医療・遺伝子改変等の広範な領域におけるキーコンセプトとしての「ヒト胚の道徳的地位」，種々の宣言等で使用されながら意味が曖昧な「人間の尊厳」を多角的に考察する。.

本書ではデータ解析にもとづく倫理学の理論の概要を述べるとともに，総計6,000名にのぼる高校生等への意識調査の結果を踏まえた，自己決定の時代の現状分析を行っている。現状分析の内容は，マスコミによるイメ ージ操作の検証，個人主義的自由主義の原理であるミルの原理の受容状況や問題点，いじめの分析，他者概念の検討，大人と子供の境界の曖昧化現象の考察等であるが，それらを貫く縦糸は「自己決定」，「自由」である。 また現代は，生命や環境，情報といった領域で，社会のレベルでも自己決定する必要に迫られている。本書の提唱するところの調査にもとづく倫理学の方法は，いわゆる「反省的均衡」の方法を実行可能にするものであり， 社会的自己決定を導く有力な方法である。.

The scientific, ethical, and policy issues raised by research involving the engraftment of human neural stem cells into the brains of nonhuman primates are explored by an interdisciplinary working group in this Policy Forum. The authors consider the possibility that this research might alter the cognitive capacities of recipient great apes and monkeys, with potential significance for their moral status.

Recently, agent technologies have attracted a lot of interest as an emerging programming paradigm. With such agent technologies, services are provided through collaboration among agents. At the same time, the spread of mobile technologies and communication infrastructures has made it possible to access the network anytime and from anywhere. Using agents and mobile technologies to realize ubiquitous computing systems, we propose a new framework based on KODAMA and VPC. KODAMA provides distributed management mechanisms by using the concept of community and (...) communication infrastructure to deliver messages among agents without agents being aware of the physical network. VPC provides a method of defining peer-to-peer services based on agent communication with policy packages. By merging the characteristics of both KODAMA and VPC functions, we propose a new framework for ubiquitous computing environments. It provides distributed management functions according to the concept of agent communities, agent communications which are abstracted from the physical environment, and agent collaboration with policy packages. Using our new framework, we conducted a large-scale experiment in shopping malls in Nagoya, which sent advertisement e-mails to users' cellular phones according to user location and attributes. The empirical results showed that our new framework worked effectively for sales in shopping malls. (shrink)

熊本大学生命倫理論集第3巻のテーマは「生命の価値」そのものである。生命倫理が前提とする生命という価値についての根本的問いかけに、哲学、倫理学、法学、医学、脳科学、生物学等の様々な分野の専門家が本気で取 り組み、学問の境界を越えた議論を展開する。.

After years of the welfare state, the rise of technology, combined with neoliberal governmental apparatuses, has established a new society of the precarious. In this new way of the world, productivity is not just connected to labor in the traditional sense of work hours, but more totally, to the formation of the self: work becomes performative and affective, and personal identities seep more and more into working ones. This new mode of being has another side, however: it can lead to (...) new forms of self-organization, resistance and exodus. In it we see the emergence of a new and disobedient self-government of the precarious. (shrink)

The Occupy movements in 2011 – this essay focuses mainly on Spain and the United States – have been more than moments of grassroots or direct democracy: they have been collective political practices testing forms of non-representationist democracy in the Europe of representative democracy to an unusually great extent. The precarious subjects of post-Fordism rejected political representation, and at the same time they struggled for a ‘real’ democracy. This oxymoron between representation and democracy structures the political philosophy of Jacques Rancière (...) and corresponds with his well-known distinction between police and politics. This is one of the reasons why his thinking is helpful to understand them as decidedly political ones. However, the assembly as one of the central topoi of theories of democracy plays no prominent role in Rancière’s political philosophy. In contrast to this, I focus on the central practice of the assemblies in the Occupy movements and develop a concept of presentist democracy. (shrink)

A historical investigation of the exclusion of Africa and Asia from modern histories of philosophy.

本书精辟阐述朝鲜朱子学集大成者-李退溪的主敬哲学的形成、发展过程,思想体系特点及其影响等。.

Precarisation means more than insecure jobs, more than the lack of security given by waged employment. By way of insecurity and danger it embraces the whole of existence, the body, modes of subjectivation. It is threat and coercion, even while it opens up new possibilities of living and working. Precarisation means living with the unforeseeable, with contingency. In this article I analyse how the new precarious living and working conditions and the privatisation of protection against precariousness are conditions of both (...) a prospering financial capitalism and its concomitant debt economy. This economy is based on the expansion of productivity that involves less work, in the traditional sense, than subjectivation. A new subjectivity is needed to assume responsibility, to take on debt, and to internalise the risks both as guilt and as debt: a personality that is doubly indebted and responsible for oneself.La precarización significa más que empleos inseguros, más que la falta de seguridad que proporciona el empleo asalariado. A través de la inseguridad y el peligro, la precarización abarca toda la existencia, el cuerpo, los modos de subjetivación. Es una amenaza y una forma de coerción, aunque también abre nuevas posibilidades de vivir y trabajar. Precarización significa vivir con lo imprevisible, bajo la contingencia. En este artículo analizo cómo las nuevas condiciones de vida y de trabajo precarias y la privatización de la protección contra la precariedad son condiciones, tanto de un próspero capitalismo financiero, como de su concomitante economía de la deuda. Esta economía se basa en la expansión de la productividad, la cual implica más bien procesos de subjetivación que lo que hemos entendido por trabajo en el sentido tradicional. Se necesita una nueva subjetividad para asumir responsabilidades, para endeudarse e internalizar los riesgos como culpa y como deuda: una personalidad doblemente endeudada y responsable de sí misma. (shrink)

Previous research suggested a role of gaze in preference formation, not merely as an expression of preference, but also as a causal influence. According to the gaze cascade hypothesis, the longer subjects look at an item, the more likely they are to develop a preference for it. However, to date the connection between viewing and liking has been investigated predominately with self-paced viewing conditions in which the subjects were required to select certain items from simultaneously presented stimuli on the basis (...) of perceived visual attractiveness. Such conditions might promote a default, but non-mandatory connection between viewing and liking. To explore whether the connection is separable, we examined the evaluative processing of single naturalistic food images in a 2 x 2 design, conducted completely within subjects, in which we varied both the type of exposure (self-paced versus time-controlled) and the type of evaluation (non-exclusive versus exclusive). In the self-paced exclusive evaluation, longer viewing was associated with a higher likelihood of a positive evaluation. However, in the self-paced non-exclusive evaluation, the trend reversed such that longer viewing durations were associated with lesser ratings. Furthermore, in the time-controlled tasks, both with non-exclusive and exclusive evaluation, there was no significant relationship between the viewing duration and the evaluation. The overall pattern of results was consistent for viewing times measured in terms of exposure duration (i.e., the duration of stimulus presentation on the screen) and in terms of actual gaze duration (i.e., the amount of time the subject effectively gazed at the stimulus on the screen). The data indicated that viewing does not intrinsically lead to a higher evaluation when evaluating single food images; instead, the relationship between viewing duration and evaluation depends on the type of task. We suggest that self-determination of exposure duration may be a prerequisite for any influence from viewing time on evaluative processing, regardless of whether the influence is facilitative. Moreover, the purported facilitative link between viewing and liking appears to be limited to exclusive evaluation, when only a restricted number of items can be included in a chosen set. (shrink)

Lorey develops an original concept of a presentist democracy based on care and interrelatedness.

We conduct an online survey experiment to determine the influence of multifunctionality recognition in agriculture on the price premiums of environmental-friendly agricultural products. We use the case of fish-friendly rice produced in Shiga prefecture, Japan, which contributes to the conservation of the water and ecosystem in rural areas around Lake Biwa by setting up fish ways and reducing the use of herbicides. We assume two conditions for consumers to pay premiums on environmental-friendly agricultural products. The first is that consumers recognize (...) multifunctionality in agriculture. The second condition is that consumers have a correct understanding of environment-friendly agricultural products. We thus examine the effects of respondents’ attributes on their responses to two types of visual stimuli: one associated with the multifunctionality of agriculture and information about environment-friendly agricultural products. In the analysis of the respondents; willingness to pay, the price premium of the group with both the stimulus and information is significantly higher than the price premium of the control group with no interventions. However, the price premium of the group with only the stimulus is not statistically different for the control group. The policy implication of this research is that consumers are more likely to support agri-environmental policies if they recognize both the multifunctionality of agriculture and the properties of environmental-friendly agricultural products. The two types of stimuli have complimentary effects on increasing price premiums. Promoting the recognition of multifunctionality is especially important for those who do not usually access information on agriculture. (shrink)

Specificities of enzymes involved in plant specialized metabolism, including flavonoid biosynthesis, are generally promiscuous. This enzyme promiscuity has served as an evolutionary basis for new enzyme functions and metabolic pathways in land plants adapting to environmental challenges. This phenomenon may lead, however, to inefficiency in specialized metabolism and adversely affect metabolite‐mediated plant survival. How plants manage enzyme promiscuity for efficient specialized metabolism is, thus, an open question. Recent studies of flavonoid biosynthesis addressing this issue have revealed a conserved strategy, namely, (...) a homolog of chalcone isomerase with no catalytic activity binds to chalcone synthase, a key flavonoid pathway enzyme, to narrow (or rectify) the enzyme's highly promiscuous product specificity. Reducing promiscuity via specific protein–protein interactions among metabolic enzymes and proteins may be a solution adopted by land plants to achieve efficient operation of specialized metabolism, while the intrinsic promiscuity of enzymes has likely been retained incidentally. (shrink)

We investigated whether the inferior parietal lobule (IPL) responds in real-time to multisensory inconsistency during movement. The IPL is thought to be involved in both the detection of inconsistencies in multisensory information obtained during movement and that obtained during self-other discrimination. However, because of the limited temporal resolution of conventional neuroimaging techniques, it is difficult to distinguish IPL activity during movement from that during self-other discrimination. We simultaneously conducted electroencephalography (EEG) and near-infrared spectroscopy (NIRS) with the goal of examining IPL (...) activity with a high spatiotemporal resolution during single reaching movements. Under a visual feedback-delay condition, gamma event-related synchronization (γ-ERS), i.e., an increase in gamma (31–47 Hz) EEG power, occurred during reaching movements. This γ-ERS is considered to reflect processing of information about prediction errors. To integrate this temporal information with spatial information from the NIRS signals, we developed a new analysis technique that enabled estimation of the regions that show a hemodynamic response characterized by EEG fluctuation present in the visual feedback-delay condition. As a result, IPL activity was explained by γ-ERS specific to visual feedback delay during movements. Thus, we succeeded in demonstrating real-time activation of the IPL in response to multisensory inconsistency. However, we did not find any correlation between either IPL activity or γ-ERS with the sense of agency. Therefore, our results suggest that while the IPL is influenced by prediction error signals, it does not engage in direct processing underlying the conscious experience of making a movement, which is the foundation of self-other discrimination. (shrink)

In their examination of elementary science classrooms, Amerine and Bilmes (1988) found that following instructions requires students to understand the relationship between the projected outcome and the corresponding course of actions. One of the most important resources for instructions is the lesson plan, which prescribes the sequence of teaching. However, there is often a gap between what is planned and what actually happens in the classroom. This raises the question of how teachers come to terms with contingent variants and unexpected (...) outcomes that real-time interactions occasion and how lesson plans are configured into these processes. This study examines a teacher education program that uses lesson plans as a central resource for teaching mathematics. The results suggest that classroom teachers use lesson plans as communicative resources to identify problems, specify assumptions about their teaching and act on the evolving contingency of classroom interaction. The interactional contingency is the locus of teaching practices, not an obstacle to the application of procedures in lesson plans. (shrink)

We study L∞κ-freeness in the variety of Boolean algebras. It is shown that some of the theorems on L∞κ-free algebras which are known to hold in varieties such as groups, abelian groups etc. are also true for Boolean algebras. But we also investigate properties such as the ccc of L∞κ-free Boolean algebras which have no counterpart in the varieties above.

Anthropology of Consciousness, Volume 31, Issue 1, Page 5-62, Spring 2020.

How (Not) to Be Secular is what Jamie Smith calls "your hitchhiker's guide to the present" -- it is both a reading guide to Charles Taylor's monumental work A Secular Age and philosophical guidance on how we might learn to live in our times. Taylor's landmark book A Secular Age (2007) provides a monumental, incisive analysis of what it means to live in the post-Christian present -- a pluralist world of competing beliefs and growing unbelief. Jamie Smith's book is a (...) compact field guide to Taylor's insightful study of the secular, making that very significant but daunting work accessible to a wide array of readers. Even more, though, Smith's How (Not) to Be Secular is a practical philosophical guidebook, a kind of how-to manual on how to live in our secular age. It ultimately offers us an adventure in self-understanding and maps out a way to get our bearings in today's secular culture, no matter who "we" are -- whether believers or skeptics, devout or doubting, self-assured or puzzled and confused. This is a book for any thinking person to chew on. (shrink)

Psychological research on people’s understanding of natural language connectives has traditionally used truth table tasks, in which participants evaluate the truth or falsity of a compound sentence given the truth or falsity of its components in the framework of propositional logic. One perplexing result concerned the indicative conditional if A then C which was often evaluated as true when A and C are true, false when A is true and C is false but irrelevant“ (devoid of value) when A is (...) false (whatever the value of C). This was called the “psychological defective table of the conditional.” Here we show that far from being anomalous the “defective” table pattern reveals a coherent semantics for the basic connectives of natural language in a trivalent framework. This was done by establishing participants’ truth tables for negation, conjunction, disjunction, conditional, and biconditional, when they were presented with statements that could be certainly true, certainly false, or neither. We review systems of three-valued tables from logic, linguistics, foundations of quantum mechanics, philosophical logic, and artificial intelligence, to see whether one of these systems adequately describes people’s interpretations of natural language connectives. We find that de Finetti’s (1936/1995) three-valued system is the best approximation to participants’ truth tables. (shrink)